Phenotypes associated with this allele

• Allele Symbol: Wdr59^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548803
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Wdr59^tm1b(EUCOMM)Wtsi/Wdr59^tm1b(EUCOMM)Wtsi	C57BL/6N-Wdr59^tm1b(EUCOMM)Wtsi/Wtsi	MGI:5757885
ht2	Wdr59^tm1b(EUCOMM)Wtsi/Wdr59^+	C57BL/6N-Wdr59^tm1b(EUCOMM)Wtsi/Wtsi	MGI:5767844

Genotype
MGI:5757885

hm1

• Allelic Composition: Wdr59^{tm1b(EUCOMM)Wtsi}/Wdr59^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Wdr59^{tm1b(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0596_2_B08

Data Sources

IMPC Data for Wdr59

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

embryonic growth retardation ( J:211773 )

IMPC - BCM

abnormal embryo size ( J:211773 )

IMPC - BCM

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - BCM

abnormal embryo size ( J:211773 )

IMPC - BCM

mortality/aging

prenatal lethality ( J:211773 )

IMPC - BCM

prenatal lethality prior to heart atrial septation ( J:211773 )

IMPC - BCM

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

Genotype
MGI:5767844

ht2

• Allelic Composition: Wdr59^{tm1b(EUCOMM)Wtsi}/Wdr59⁺
• Genetic Background: C57BL/6N-Wdr59^{tm1b(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0596_2_B08

Data Sources

IMPC Data for Wdr59

hematopoietic system

decreased erythrocyte cell number ( J:211773 )

♂

IMPC - BCM

decreased hematocrit ( J:211773 )

♂

IMPC - BCM

decreased hemoglobin content ( J:211773 )

♂

IMPC - BCM

decreased leukocyte cell number ( J:211773 )

IMPC - BCM

immune system

decreased leukocyte cell number ( J:211773 )

IMPC - BCM