Phenotypes associated with this allele

• Allele Symbol: Atxn7l3^{tm1.1(KOMP)Wtsi}
• Allele Name: targeted mutation 1.1, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548884
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Atxn7l3^tm1.1(KOMP)Wtsi/Atxn7l3^tm1.1(KOMP)Wtsi	C57BL/6N-Atxn7l3^tm1.1(KOMP)Wtsi/Ics	MGI:5756773
ht2	Atxn7l3^tm1.1(KOMP)Wtsi/Atxn7l3^+	C57BL/6N-Atxn7l3^tm1.1(KOMP)Wtsi/Ics	MGI:5756772

Genotype
MGI:5756773

hm1

• Allelic Composition: Atxn7l3^{tm1.1(KOMP)Wtsi}/Atxn7l3^{tm1.1(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Atxn7l3^{tm1.1(KOMP)Wtsi}/Ics
• Cell Lines: EPD0321_4_E11

Data Sources

IMPC Data for Atxn7l3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - ICS

Genotype
MGI:5756772

ht2

• Allelic Composition: Atxn7l3^{tm1.1(KOMP)Wtsi}/Atxn7l3⁺
• Genetic Background: C57BL/6N-Atxn7l3^{tm1.1(KOMP)Wtsi}/Ics
• Cell Lines: EPD0321_4_E11

Data Sources

IMPC Data for Atxn7l3

behavior/neurological

abnormal vocalization ( J:211773 )

IMPC - ICS

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

♂

IMPC - ICS

abnormal retina blood vessel morphology ( J:211773 )

♂

IMPC - ICS

integument

abnormal coat/hair pigmentation ( J:211773 )

♂

IMPC - ICS

limbs/digits/tail

short tibia ( J:211773 )

IMPC - ICS

pigmentation

abnormal coat/hair pigmentation ( J:211773 )

♂

IMPC - ICS

skeleton

short tibia ( J:211773 )

IMPC - ICS

vision/eye

abnormal retina vasculature morphology ( J:211773 )

♂

IMPC - ICS

abnormal retina blood vessel morphology ( J:211773 )

♂

IMPC - ICS

decreased total retina thickness ( J:211773 )

♂

IMPC - ICS