Phenotypes associated with this allele

• Allele Symbol: Zbtb24^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5548888
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Zbtb24^tm1b(EUCOMM)Hmgu/Zbtb24^tm1b(EUCOMM)Hmgu	C57BL/6N-Zbtb24^tm1b(EUCOMM)Hmgu/Ieg	MGI:5757902
ht2	Zbtb24^tm1b(EUCOMM)Hmgu/Zbtb24^+	C57BL/6N-Zbtb24^tm1b(EUCOMM)Hmgu/Ieg	MGI:5757901

Genotype
MGI:5757902

hm1

• Allelic Composition: Zbtb24^{tm1b(EUCOMM)Hmgu}/Zbtb24^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Zbtb24^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0652_2_E10

Data Sources

IMPC Data for Zbtb24

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:5757901

ht2

• Allelic Composition: Zbtb24^{tm1b(EUCOMM)Hmgu}/Zbtb24⁺
• Genetic Background: C57BL/6N-Zbtb24^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0652_2_E10

Data Sources

IMPC Data for Zbtb24

behavior/neurological

increased startle reflex ( J:211773 )

♂

IMPC - HMGU

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

♂

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

♂

IMPC - HMGU

hematopoietic system

decreased red blood cell distribution width ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

increased circulating HDL cholesterol level ( J:211773 )

IMPC - HMGU

decreased circulating chloride level ( J:211773 )

IMPC - HMGU

vision/eye

abnormal retina vasculature morphology ( J:211773 )

♂

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

♂

IMPC - HMGU

abnormal lens morphology ( J:211773 )

♀

IMPC - HMGU