Phenotypes associated with this allele

• Allele Symbol: Gad2^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548938
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gad2^tm1b(EUCOMM)Wtsi/Gad2^tm1b(EUCOMM)Wtsi	C57BL/6N-Gad2^tm1b(EUCOMM)Wtsi/Ieg	MGI:5757151

Genotype
MGI:5757151

hm1

• Allelic Composition: Gad2^{tm1b(EUCOMM)Wtsi}/Gad2^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Gad2^{tm1b(EUCOMM)Wtsi}/Ieg
• Cell Lines: EPD0363_5_D12

Data Sources

IMPC Data for Gad2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal behavior ( J:211773 )

♂

IMPC - HMGU

decreased exploration in new environment ( J:211773 )

♀

IMPC - HMGU

increased anxiety-related response ( J:211773 )

♂

IMPC - HMGU

increased thigmotaxis ( J:211773 )

♂

IMPC - HMGU

increased vertical activity ( J:211773 )

♀

IMPC - HMGU

decreased locomotor activity ( J:211773 )

♂

IMPC - HMGU

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

IMPC - HMGU

increased circulating sodium level ( J:211773 )

♀

IMPC - HMGU

increased circulating alkaline phosphatase level ( J:211773 )

♂

IMPC - HMGU

decreased respiratory quotient ( J:211773 )

IMPC - HMGU

impaired glucose tolerance ( J:211773 )

♂

IMPC - HMGU

increased circulating chloride level ( J:211773 )

♂

IMPC - HMGU

nervous system

decreased prepulse inhibition ( J:211773 )

♂

IMPC - HMGU