All Phenotypes Scn4a<tm2b(KOMP)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Scn4a^{tm2b(KOMP)Wtsi}
targeted mutation 2b, Wellcome Trust Sanger Institute
MGI:5548971

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Scn4a^{tm2b(KOMP)Wtsi}/Scn4a^{tm2b(KOMP)Wtsi}	C57BL/6N-Scn4a^{tm2b(KOMP)Wtsi}/H	MGI:5757681
ht2	Scn4a^{tm2b(KOMP)Wtsi}/Scn4a⁺	C57BL/6N-Scn4a^{tm2b(KOMP)Wtsi}/H	MGI:5757680

Allelic Composition	Scn4a^{tm2b(KOMP)Wtsi}/Scn4a^{tm2b(KOMP)Wtsi}
Genetic Background	C57BL/6N-Scn4a^{tm2b(KOMP)Wtsi}/H
Cell Lines	EPD0846_1_H11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn4a^{tm2b(KOMP)Wtsi} mutation (0 available); any Scn4a mutation (71 available)

Data Sources

IMPC Data for Scn4a

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Allelic Composition	Scn4a^{tm2b(KOMP)Wtsi}/Scn4a⁺
Genetic Background	C57BL/6N-Scn4a^{tm2b(KOMP)Wtsi}/H
Cell Lines	EPD0846_1_H11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn4a^{tm2b(KOMP)Wtsi} mutation (0 available); any Scn4a mutation (71 available)

Data Sources

IMPC Data for Scn4a

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

decreased mean platelet volume ( J:211773 )

IMPC - HAR

homeostasis/metabolism

decreased circulating alkaline phosphatase level ( J:211773 )

IMPC - HAR

increased circulating amylase level ( J:211773 )

IMPC - HAR

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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