Phenotypes associated with this allele

• Allele Symbol: Abca1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5548975
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Abca1^tm1b(EUCOMM)Hmgu/Abca1^tm1b(EUCOMM)Hmgu	C57BL/6N-Abca1^tm1b(EUCOMM)Hmgu/Bay	MGI:5756633
ht2	Abca1^tm1b(EUCOMM)Hmgu/Abca1^+	C57BL/6N-Abca1^tm1b(EUCOMM)Hmgu/Bay	MGI:5756632

Genotype
MGI:5756633

hm1

• Allelic Composition: Abca1^{tm1b(EUCOMM)Hmgu}/Abca1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Abca1^{tm1b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0720_5_A09

Data Sources

IMPC Data for Abca1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

embryo

abnormal embryo size ( J:211773 )

IMPC - BCM

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - BCM

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

Genotype
MGI:5756632

ht2

• Allelic Composition: Abca1^{tm1b(EUCOMM)Hmgu}/Abca1⁺
• Genetic Background: C57BL/6N-Abca1^{tm1b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0720_5_A09

Data Sources

IMPC Data for Abca1

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

vision/eye

abnormal retina morphology ( J:211773 )

♀

IMPC - BCM