Analysis Tools|
Allele Symbol Allele Name Allele ID |
Igh-Jtm2.1(4E10)Lave targeted mutation 2.1, Laurent Verkoczy MGI:5550246 |
||||||||||||
| Summary |
2 genotypes
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• B cell development is blocked at the small pre-B to immature B transition
|
|
• B cell development is blocked at the small pre-B to immature B transition
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• modest blockage at the pro/large pre-B to small pre-B transition
|
|
• B cell development is blocked at the small pre-B to immature B transition
|
|
• B cells exhibit elevated basal activation and muted response to BCR ligation
|
|
• modest blockage at the pro/large pre-B to small pre-B transition
|
|
• B cell development is blocked at the small pre-B to immature B transition
|
|
• B cells exhibit elevated basal activation and muted response to BCR ligation
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 10/22/2024 MGI 6.24 |
|
|
|
||
