About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ghrtm1c(KOMP)Wtsi
targeted mutation 1c, Wellcome Trust Sanger Institute
MGI:5550361
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Ghrtm1c(KOMP)Wtsi/Ghrtm1c(KOMP)Wtsi
Tg(Fabp4-cre)1Rev/0
involves: C57BL/6N MGI:5550143


Genotype
MGI:5550143
cn1
Allelic
Composition
Ghrtm1c(KOMP)Wtsi/Ghrtm1c(KOMP)Wtsi
Tg(Fabp4-cre)1Rev/0
Genetic
Background
involves: C57BL/6N
Cell Lines EPD0125_5_H05
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ghrtm1c(KOMP)Wtsi mutation (1 available); any Ghr mutation (50 available)
Tg(Fabp4-cre)1Rev mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
adipose tissue
• at 2 months in male mice
• at 4 months in female mice
• in subcutaneous and perigonadal fat pads
• in female, but not male, mice

homeostasis/metabolism
N
• mice exhibit normal glucose homeostasis
• in female, but not male, mice
• in female, but not male, mice
• mice exhibit increased fluid mass
• slightly decreased in the serum of male, but not female, mice

growth/size/body
• at 10 months in male mice
• at 5 to 10 months in female mice
• by 3 months in male mice
• by 5 months in female mice
• in female, but not male, mice

immune system
• in male, but not female, mice
• in female, but not male, mice

renal/urinary system
• in female, but not male, mice

muscle
• in female, but not male, mice

integument

hematopoietic system
• in male, but not female, mice

limbs/digits/tail
• in female, but not male, mice





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory