Phenotypes associated with this allele

• Allele Symbol: Tmem43^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5550594
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tmem43^tm1b(EUCOMM)Wtsi/Tmem43^tm1b(EUCOMM)Wtsi	involves: C57BL/6 * C57BL/6N * CBA	MGI:6358317

Genotype
MGI:6358317

hm1

• Allelic Composition: Tmem43^{tm1b(EUCOMM)Wtsi}/Tmem43^{tm1b(EUCOMM)Wtsi}
• Genetic Background: involves: C57BL/6 * C57BL/6N * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:267849 )

N • normal heart function according to echocardiography up to age 20 months

N • normal LVIDd, LVIDs, LVPWd and IVSd

N • normal remodeling response to transverse aortic restriction (TAC)

N • normal response to beta-adrenergic stimulation with dobutamine

embryo

embryo phenotype ( J:267849 )

N • mice born at expected Mendelian ratio

mortality/aging

mortality/aging ( J:267849 )

N • viable