Phenotypes associated with this allele

• Allele Symbol: Ap2b1^b2b2321Clo
• Allele Name: Bench to Bassinet Program (B2B/CVDC), mutation 2321 Cecilia Lo
• Allele ID: MGI:5552944
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ap2b1^b2b2321Clo/Ap2b1^b2b2321Clo	C57BL/6J-Ap2b1^b2b2321Clo	MGI:5554204

Genotype
MGI:5554204

hm1

• Allelic Composition: Ap2b1^b2b2321Clo/Ap2b1^b2b2321Clo
• Genetic Background: C57BL/6J-Ap2b1^b2b2321Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 2321-006-MNE is shows an anterior aorta, RAA, and biventricular hypertrophy which is diagnosed as Taussig-Bing type DORV by EFIC imaging

cardiovascular system

abnormal aortic arch morphology ( J:175213 )

right aortic arch ( J:175213 )

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )

double outlet right ventricle with atrioventricular septal defect ( J:175213 )

double outlet right ventricle, Taussig bing type ( J:175213 )

overriding aortic valve ( J:175213 )

atrioventricular septal defect ( J:175213 )

perimembraneous ventricular septal defect ( J:175213 )

craniofacial

micrognathia ( J:175213 )

cleft palate ( J:175213 )

digestive/alimentary system

cleft palate ( J:175213 )

hematopoietic system

thymus hypoplasia ( J:175213 )

immune system

thymus hypoplasia ( J:175213 )

skeleton

micrognathia ( J:175213 )

endocrine/exocrine glands

thymus hypoplasia ( J:175213 )

growth/size/body

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )

cleft palate ( J:175213 )

muscle

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )