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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Eif3mtm1Nju
targeted mutation 1, Model Animal Research Center of Nanjing University
MGI:5553067
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Eif3mtm1Nju/Eif3mtm1.1Nju involves: 129 * FVB/N MGI:5553076
cn2
 		Eif3mtm1Nju/Eif3mtm1Nju involves: 129 MGI:5553079
cn3
 		Eif3mtm1Nju/Eif3mtm1Nju
Tg(Fabp4-cre)1Rev/0 		involves: 129 * FVB/N MGI:5553078


Genotype
MGI:5553076
ht1
Allelic
Composition		 Eif3mtm1Nju/Eif3mtm1.1Nju
Genetic
Background		 involves: 129 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eif3mtm1.1Nju mutation (0 available); any Eif3m mutation (19 available)
Eif3mtm1Nju mutation (0 available); any Eif3m mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Severe growth retardation in Eif3mtm1Nju/Eif3mtm1.1Nju embryos at E9.5.

mortality/aging
preweaning lethality, complete penetrance ( J:204915 )
• no postnatal mice are recovered

embryo
embryonic growth retardation ( J:204915 )
• severe at E9.5

growth/size/body
embryonic growth retardation ( J:204915 )
• severe at E9.5




Genotype
MGI:5553079
cn2
Allelic
Composition		 Eif3mtm1Nju/Eif3mtm1Nju
Genetic
Background		 involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eif3mtm1Nju mutation (0 available); any Eif3m mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:204915 )
• within 2 week after adenoviral cre administration

growth/size/body
decreased body weight ( J:204915 )
• 1 week after adenoviral cre administration

liver/biliary system
abnormal liver morphology ( J:204915 )
• reduced liver protein synthesis after adenoviral cre administration




Genotype
MGI:5553078
cn3
Allelic
Composition		 Eif3mtm1Nju/Eif3mtm1Nju
Tg(Fabp4-cre)1Rev/0
Genetic
Background		 involves: 129 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eif3mtm1Nju mutation (0 available); any Eif3m mutation (19 available)
Tg(Fabp4-cre)1Rev mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Severe growth retardation in Eif3mtm1Nju/Eif3mtm1Nju Tg(Fabp4-cre)1Rev/0 embryos at E9.5

mortality/aging

embryo
embryonic growth retardation ( J:204915 )
• severe at E9.5, but not as severe as in Eif3mtm1Nju/Eif3mtm1Nju Tg(Fabp4-cre)1Rev mice

growth/size/body
embryonic growth retardation ( J:204915 )
• severe at E9.5, but not as severe as in Eif3mtm1Nju/Eif3mtm1Nju Tg(Fabp4-cre)1Rev mice




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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory