All Phenotypes Eif3m<tm1.1Nju> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Eif3m^tm1.1Nju
targeted mutation 1.1, Model Animal Research Center of Nanjing University
MGI:5553070

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Eif3m^tm1.1Nju/Eif3m^tm1.1Nju	involves: 129 * FVB/N	MGI:5553077
ht2	Eif3m^tm1.1Nju/Eif3m⁺	involves: 129 * FVB/N	MGI:5553080
ht3	Eif3m^tm1Nju/Eif3m^tm1.1Nju	involves: 129 * FVB/N	MGI:5553076

Allelic Composition	Eif3m^tm1.1Nju/Eif3m^tm1.1Nju
Genetic Background	involves: 129 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eif3m^tm1.1Nju mutation (0 available); any Eif3m mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:204915 )

• no mice are recovered at E9.5

Allelic Composition	Eif3m^tm1.1Nju/Eif3m⁺
Genetic Background	involves: 129 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eif3m^tm1.1Nju mutation (0 available); any Eif3m mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Decreased fat pad size in Eif3m^tm1.1Nju/Eif3m⁺ mice

liver/biliary system

liver/biliary system phenotype ( J:204915 )

N	• livers exhibit normal cell size

decreased liver weight ( J:204915 )

adipose tissue

adipose tissue phenotype ( J:204915 )

N	• subscapular fat pads exhibit normal cell size

decreased total fat pad weight ( J:204915 )

renal/urinary system

decreased kidney weight ( J:204915 )

growth/size/body

decreased body weight ( J:204915 )

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:204915 )

N	• mice exhibit normal blood glucose, aspartate transaminase and alanine transaminase

behavior/neurological

behavior/neurological phenotype ( J:204915 )

N	• food intake is normal

Allelic Composition	Eif3m^tm1Nju/Eif3m^tm1.1Nju
Genetic Background	involves: 129 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eif3m^tm1.1Nju mutation (0 available); any Eif3m mutation (19 available)
Eif3m^tm1Nju mutation (0 available); any Eif3m mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Severe growth retardation in Eif3m^tm1Nju/Eif3m^tm1.1Nju embryos at E9.5.

mortality/aging

preweaning lethality, complete penetrance ( J:204915 )

• no postnatal mice are recovered

embryo

embryonic growth retardation ( J:204915 )

• severe at E9.5

growth/size/body

embryonic growth retardation ( J:204915 )

• severe at E9.5

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