About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Eif3mtm1.1Nju
targeted mutation 1.1, Model Animal Research Center of Nanjing University
MGI:5553070
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Eif3mtm1.1Nju/Eif3mtm1.1Nju involves: 129 * FVB/N MGI:5553077
ht2
 		Eif3mtm1.1Nju/Eif3m+ involves: 129 * FVB/N MGI:5553080
ht3
 		Eif3mtm1Nju/Eif3mtm1.1Nju involves: 129 * FVB/N MGI:5553076


Genotype
MGI:5553077
hm1
Allelic
Composition		 Eif3mtm1.1Nju/Eif3mtm1.1Nju
Genetic
Background		 involves: 129 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eif3mtm1.1Nju mutation (0 available); any Eif3m mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:204915 )
• no mice are recovered at E9.5




Genotype
MGI:5553080
ht2
Allelic
Composition		 Eif3mtm1.1Nju/Eif3m+
Genetic
Background		 involves: 129 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eif3mtm1.1Nju mutation (0 available); any Eif3m mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Decreased fat pad size in Eif3mtm1.1Nju/Eif3m+ mice

liver/biliary system
liver/biliary system phenotype ( J:204915 )
N
• livers exhibit normal cell size

adipose tissue
adipose tissue phenotype ( J:204915 )
N
• subscapular fat pads exhibit normal cell size

renal/urinary system

growth/size/body
decreased body weight ( J:204915 )

homeostasis/metabolism
homeostasis/metabolism phenotype ( J:204915 )
N
• mice exhibit normal blood glucose, aspartate transaminase and alanine transaminase

behavior/neurological
behavior/neurological phenotype ( J:204915 )
N
• food intake is normal




Genotype
MGI:5553076
ht3
Allelic
Composition		 Eif3mtm1Nju/Eif3mtm1.1Nju
Genetic
Background		 involves: 129 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eif3mtm1.1Nju mutation (0 available); any Eif3m mutation (19 available)
Eif3mtm1Nju mutation (0 available); any Eif3m mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Severe growth retardation in Eif3mtm1Nju/Eif3mtm1.1Nju embryos at E9.5.

mortality/aging
preweaning lethality, complete penetrance ( J:204915 )
• no postnatal mice are recovered

embryo
embryonic growth retardation ( J:204915 )
• severe at E9.5

growth/size/body
embryonic growth retardation ( J:204915 )
• severe at E9.5




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory