mortality/aging
• mice die within 24 hours of birth
|
cardiovascular system
• contains scattered clusters of densely packed nucleated erythroid cells covered by a continuous layer of epicardial layer without pericardial hemorrhage
|
• reduced surface area coverage of the subepicardial coronary vascular plexus at E12.5
• disorganized coronary vascular plexus at E14.5
• however, arterial-venous specification of coronary endothelial cells is normal
|
• fewer large diameter coronary vessels in the subepicardium and ventricular septum at E18.5
|
• irregular covering of the heart at E12.5
• occasional cyst-like protrusions at E12.5
|
growth/size/body
• small chest cavity
|
renal/urinary system
respiratory system
skeleton
• fusion bands of the proximal ribs
• misshapen distal ribs with evidence of distal rib fusions
|
rib fusion
(
J:203805
)
• fusion bands of the proximal ribs
• misshapen distal ribs with evidence of distal rib fusions
|
• absent or reduced
|
• absent or reduced
|
muscle
• contains scattered clusters of densely packed nucleated erythroid cells covered by a continuous layer of epicardial layer without pericardial hemorrhage
|