Phenotypes associated with this allele

• Allele Symbol: qvyr
• Allele Name: quivery runt
• Allele ID: MGI:5554211
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	qvyr/qvyr	B6(Cg)-qvyr/GrsrJ	MGI:5750968

Genotype
MGI:5750968

hm1

• Allelic Composition: qvyr/qvyr
• Genetic Background: B6(Cg)-qvyr/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hearing/vestibular/ear

increased or absent threshold for auditory brainstem response ( J:207002 )

• some, but not all, homozygotes have severe hearing loss, with one homozygote at 3.5 weeks of age showing severe hearing loss, and two of four at approximately 3 weeks of age showing severe hearing loss while one had milde hearing loss and the fourth had normal hearing.

• the loss of hearing may parallel the disease progression

behavior/neurological

tremors ( J:207002 )

• quivering movement by 3 weeks of age, progresses rapidly until premature death any time after wean age

mortality/aging

premature death ( J:207002 )

• homozygotes die anytime after wean age and only a few have survived to 10 weeks of age

growth/size/body

decreased body size ( J:207002 )

• runted appearance by 3 weeks of age