reproductive system
small testis
(
J:198777
)
• testes of mature males are small relative to controls
|
• testis weight increases similar to controls in initial 3-4 weeks of age, then begins to decline and remains low in adult males
|
• when males are housed with wild-type females for 21 weeks from 4 weeks of age, each animal only sires one litter (litter is slightly decreased in size versus wild-type males); control males sire 4-6 litters over 21 week period
|
• by 2 months of age, males are sterile
|
endocrine/exocrine glands
small testis
(
J:198777
)
• testes of mature males are small relative to controls
|
• testis weight increases similar to controls in initial 3-4 weeks of age, then begins to decline and remains low in adult males
|