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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tinf2tm2.1Tdl
targeted mutation 2.1, Titia de Lange
MGI:5556226
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tinf2tm2.1Tdl/Tinf2tm2.1Tdl involves: C57BL/6 MGI:5556236
cn2
 		Tinf2tm2.1Tdl/Tinf2+
Tg(CMV-cre)1Cgn/0 		involves: BALB/cJ * C57BL/6 MGI:5556240


Genotype
MGI:5556236
hm1
Allelic
Composition		 Tinf2tm2.1Tdl/Tinf2tm2.1Tdl
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tinf2tm2.1Tdl mutation (1 available); any Tinf2 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype




Genotype
MGI:5556240
cn2
Allelic
Composition		 Tinf2tm2.1Tdl/Tinf2+
Tg(CMV-cre)1Cgn/0
Genetic
Background		 involves: BALB/cJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(CMV-cre)1Cgn mutation (6 available)
Tinf2tm2.1Tdl mutation (1 available); any Tinf2 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased birth body size ( J:207367 )
decreased body weight ( J:207367 )
• mice weigh slightly less than wild type littermates at weaning and 6 months of age

mortality/aging
prenatal lethality, incomplete penetrance ( J:207367 )
• mutants are born at a lower than expected frequency (35%)




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory