Phenotypes associated with this allele

• Allele Symbol: Dzip1^tm1.1Blnw
• Allele Name: targeted mutation 1.1, Baolin Wang
• Allele ID: MGI:5557987
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dzip1^tm1.1Blnw/Dzip1^tm1.1Blnw	involves: 129S6/SvEvTac * C57BL/6	MGI:5557996

Genotype
MGI:5557996

hm1

• Allelic Composition: Dzip1^tm1.1Blnw/Dzip1^tm1.1Blnw
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

The neural tube and somites are underdeveloped in Dzip1^tm1.1Blnw/Dzip1^tm1.1Blnw embryos

mortality/aging

embryonic lethality during organogenesis, incomplete penetrance ( J:207249 )

• 7 of 22 mice die around E9.5

embryo

decreased embryo size ( J:207249 )

• at E9.5

abnormal neural tube morphology ( J:207249 )

• underdeveloped at E9.5

abnormal somite development ( J:207249 )

• underdeveloped at E9.5

cellular

abnormal primary cilium morphology ( J:207249 )

• mouse embryonic fibroblasts lack primary cilia unlike most wild-type cells

growth/size/body

decreased embryo size ( J:207249 )

• at E9.5

nervous system

abnormal neural tube morphology ( J:207249 )

• underdeveloped at E9.5