Phenotypes associated with this allele

• Allele Symbol: Phc2^tm2.1Hko
• Allele Name: targeted mutation 2.1, Haruhiko Koseki
• Allele ID: MGI:5559318
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Phc2^tm2.1Hko/Phc2^tm2.1Hko	involves: 129S1/Sv * 129X1/SvJ	MGI:5559479
ht2	Phc2^tm2.1Hko/Phc2^+	involves: 129S1/Sv * 129X1/SvJ	MGI:5559480

Genotype
MGI:5559479

hm1

• Allelic Composition: Phc2^tm2.1Hko/Phc2^tm2.1Hko
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

increased rib number ( J:204987 )

• C7 transformation to T1 in 8 of 9 mice with ectopic ribs on C7

cervical vertebral fusion ( J:204987 )

• C1 to C2 in 8 of 9 mice

vertebral transformation ( J:204987 )

• posterior transformation of the axis as in null mice

thoracic vertebral transformation ( J:204987 )

• T13 to L1 in 7 of 9 mice

cervical vertebral transformation ( J:204987 )

• C7 to T1 in 8 of 9 mice with ectopic ribs on C7

lumbar vertebral transformation ( J:204987 )

• L6 to S1 in 6 of 9 mice

Genotype
MGI:5559480

ht2

• Allelic Composition: Phc2^tm2.1Hko/Phc2⁺
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

skeleton

increased rib number ( J:204987 )

• C7 transformation to T1 in 4 of 31 mice with ectopic ribs on C7

cervical vertebral fusion ( J:204987 )

• C1 to C2 in 4 of 31 mice

vertebral transformation ( J:204987 )

• posterior transformation of the axis as in null mice

thoracic vertebral transformation ( J:204987 )

• T13 to L1 in 5 of 31 mice

cervical vertebral transformation ( J:204987 )

• C7 to T1 in 4 of 31 mice with ectopic ribs on C7

lumbar vertebral transformation ( J:204987 )

• L6 to S1 in 11 of 31 mice