homeostasis/metabolism
• in fasted mice fed standard chow (at 3 and 16 weeks) or a high fat diet (at 28 weeks)
|
• faster glucose clearance from serum after glucose administration
|
• in fasted mice fed a high fat diet
|
• slightly in fasted mice fed a high fat diet
• however, insulin level response to blood glucose elevation is normal
|
• in mice fed a high fat diet
• however, mice fed standard chow exhibit normal glucose tolerance
|
• in mice fed a high fat diet
|
adipose tissue
• in mice fed a high fat diet
|
• mouse embryonic fibroblasts exhibit reduced differentiation into adipocytes compared with wild-type cells
|
• in mice fed standard chow
|
• in mice fed a high fat diet
|
growth/size/body
• in mice fed standard chow or a high fat diet
• in mice injected with leptin
|
• in mice fed standard chow or a high fat diet
|
behavior/neurological
• in mice fed standard chow
• in mice injected with leptin during the first dark cycle
• however, food intake of a high fat diet is normal
|