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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tspotm1.1Maf
targeted mutation 1.1, Michael A Forte
MGI:5560329
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Tspotm1.1Maf/Tspotm1.1Maf B6(129S4)-Tspotm1.1Maf MGI:5560330
cn2
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Tspotm1.1Maf/Tspotm1.1Maf
involves: C57BL/6 * DBA MGI:5588662
cn3
Tspotm1.1Maf/Tspotm1.1Maf
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+
involves: C57BL/6 * FVB/N MGI:5588664


Genotype
MGI:5560330
hm1
Allelic
Composition
Tspotm1.1Maf/Tspotm1.1Maf
Genetic
Background
B6(129S4)-Tspotm1.1Maf
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tspotm1.1Maf mutation (1 available); any Tspo mutation (16 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• mice are viable and fertile




Genotype
MGI:5588662
cn2
Allelic
Composition
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Tspotm1.1Maf/Tspotm1.1Maf
Genetic
Background
involves: C57BL/6 * DBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Speer6-ps1Tg(Alb-cre)21Mgn mutation (6 available); any Speer6-ps1 mutation (4 available)
Tspotm1.1Maf mutation (1 available); any Tspo mutation (16 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
liver/biliary system
N
• mice show normal liver morphology and liver mitochondria morphology and function




Genotype
MGI:5588664
cn3
Allelic
Composition
Tspotm1.1Maf/Tspotm1.1Maf
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+
Genetic
Background
involves: C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A1cfTg(Myh6-cre/Esr1*)1Jmk mutation (5 available); any A1cf mutation (39 available)
Tspotm1.1Maf mutation (1 available); any Tspo mutation (16 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
N
• tamoxifen treated mice show a similiar response to ischemia/reperfusion injury as controls





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory