All Phenotypes Bmpr2<b2b2556Clo> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Bmpr2^b2b2556Clo
Bench to Bassinet Program (B2B/CVDC) mutation 2556, Cecilia Lo
MGI:5560496

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Bmpr2^b2b2556Clo/Bmpr2^b2b2556Clo	C57BL/6J-Bmpr2^b2b2556Clo	MGI:5560502

Allelic Composition	Bmpr2^b2b2556Clo/Bmpr2^b2b2556Clo
Genetic Background	C57BL/6J-Bmpr2^b2b2556Clo

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmpr2^b2b2556Clo mutation (0 available); any Bmpr2 mutation (46 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Mutant 2556-004-1 (E16.5) exhibits parallel outflow tracts and ventricles appear thin which is diagnosed as PTA (Type A4) and ventricular non-copmaction by EFIC imaging and the heart is malrotated further to the left

cardiovascular system

abnormal myocardium compact layer morphology ( J:175213 )

• ventricular non-compaction

persistent truncus arteriosus type i ( J:175213 )

persistent truncus arteriosus type iv ( J:175213 )

• Type A4

atrioventricular septal defect ( J:175213 )

muscular ventricular septal defect ( J:175213 )

abnormal semilunar valve morphology ( J:175213 )

• absent semilunar valves

renal/urinary system

hydronephrosis ( J:175213 )

muscle

abnormal myocardium compact layer morphology ( J:175213 )

• ventricular non-compaction

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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