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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lrp2b2b2671Clo
Bench to Bassinet Program (B2B/CVDC), mutation 2671 Cecilia Lo
MGI:5560499
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Lrp2b2b2671Clo/Lrp2b2b2671Clo C57BL/6J-Lrp2b2b2671Clo MGI:5560504


Genotype
MGI:5560504
hm1
Allelic
Composition		 Lrp2b2b2671Clo/Lrp2b2b2671Clo
Genetic
Background		 C57BL/6J-Lrp2b2b2671Clo
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp2b2b2671Clo mutation (1 available); any Lrp2 mutation (261 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Mutant 2671-006-3 (E16.5) exhibits PTA with a RAA and thin ventricle wall which is confirmed by EFIC imaging as ventricular non-compaction

cardiovascular system
abnormal myocardium compact layer morphology ( J:175213 )
• excessive myocardial trabeculation or noncompaction
persistent truncus arteriosus ( J:175213 )
• Type A1, A2, A4

craniofacial

embryo

hematopoietic system

immune system

limbs/digits/tail

renal/urinary system

skeleton

vision/eye

endocrine/exocrine glands

growth/size/body
heart left ventricle hypertrophy ( J:175213 )
heart right ventricle hypertrophy ( J:175213 )
short snout ( J:175213 )
kidney cyst ( J:175213 )

muscle
abnormal myocardium compact layer morphology ( J:175213 )
• excessive myocardial trabeculation or noncompaction




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory