All Phenotypes Mpst<tm1Nori> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mpst^tm1Nori
targeted mutation 1, Noriyuki Nagahara
MGI:5560811

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Mpst^tm1Nori/Mpst⁺ Tg(CAG-cre)13Miya/0	involves: C57BL/6 * C57BL/6JJcl	MGI:5560978

Allelic Composition	Mpst^tm1Nori/Mpst⁺ Tg(CAG-cre)13Miya/0
Genetic Background	involves: C57BL/6 * C57BL/6JJcl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mpst^tm1Nori mutation (0 available); any Mpst mutation (23 available)
Tg(CAG-cre)13Miya mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:207803 )

N	• female mice exhibit no abnormalities

abnormal spermatocyte morphology ( J:207803 )

• severe spermatogenic hypoplasia

increased Leydig cell number ( J:207803 )

testis hypoplasia ( J:207803 )

• focal with vacuolar degeneration

male infertility ( J:207803 )

• in two-thirds of mice

endocrine/exocrine glands

increased Leydig cell number ( J:207803 )

testis hypoplasia ( J:207803 )

• focal with vacuolar degeneration

cellular

abnormal spermatocyte morphology ( J:207803 )

• severe spermatogenic hypoplasia

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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