Analysis Tools
reproductive system
| N |
• mice exhibit normal development without male infertility
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behavior/neurological
| N |
• mice exhibit normal behavior in the 3-chamber social interaction and forced-swim tests
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• reduced distance traveled during the first 9 minutes in an open field test
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• in a light-dark chamber test, mice tend to spend more time in the light chamber and tend to make fewer transitions into the dark chamber compared with wild-type mice
• in an elevated-plus maze, mice spend reduced time in the open arms compared with wild-type mice
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homeostasis/metabolism
| N |
• mice exhibit normal dopamine content in the brain
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• increased 5-HT and 5-hydroxyindoleacetic acid (5-HIAA) in the prefrontal cortex
• increased 5-HIAA in the hippocampus
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nervous system
| N |
• mice exhibit normal cerebrum, cerebellum and hippocampus area
• mice exhibit normal dopamine content in the brain
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