Phenotypes associated with this allele

• Allele Symbol: Zfp365^tm1That
• Allele Name: targeted mutation 1, Tsuyoshi Hattori
• Allele ID: MGI:5561003
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Zfp365^tm1That/Zfp365^tm1That	B6.Cg-Zfp365^tm1That	MGI:5561036

Genotype
MGI:5561036

hm1

• Allelic Composition: Zfp365^tm1That/Zfp365^tm1That
• Genetic Background: B6.Cg-Zfp365^tm1That

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:207522 )

N • mice exhibit normal chandelier cells

abnormal brain interneuron morphology ( J:207522 )

• cortical basket cells in the somatosensory cortices exhibit decreased total process length, primary and secondary branch points and reduced process complexity compared with wild-type cells

• however, the number of processes from the soma of cortical basket cells is normal and the morphology of basket cells in the visual cortex is normal

increased oligodendrocyte number ( J:207476 )

• increase in immature oligodendrocytes

abnormal myelination ( J:207476 )

• myelination in the corpus callosum is delayed during the postnatal period but recovers by adulthood such that most nerves are unmyelinated and small in diameter at P10 but normal by adulthood