Phenotypes associated with this allele

• Allele Symbol: Vps4a^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5561562
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Vps4a^tm1b(EUCOMM)Hmgu/Vps4a^tm1b(EUCOMM)Hmgu	C57BL/6N-Vps4a^tm1b(EUCOMM)Hmgu/Bay	MGI:5757881
ht2	Vps4a^tm1b(EUCOMM)Hmgu/Vps4a^+	C57BL/6N-Vps4a^tm1b(EUCOMM)Hmgu/Bay	MGI:5757880

Genotype
MGI:5757881

hm1

• Allelic Composition: Vps4a^{tm1b(EUCOMM)Hmgu}/Vps4a^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Vps4a^{tm1b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0779_2_A10

Data Sources

IMPC Data for Vps4a

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

craniofacial

protruding tongue ( J:211773 )

IMPC - BCM

digestive/alimentary system

protruding tongue ( J:211773 )

IMPC - BCM

embryo

abnormal embryo size ( J:211773 )

IMPC - BCM

growth/size/body

protruding tongue ( J:211773 )

IMPC - BCM

abnormal embryo size ( J:211773 )

IMPC - BCM

abnormal body wall morphology ( J:211773 )

IMPC - BCM

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

Genotype
MGI:5757880

ht2

• Allelic Composition: Vps4a^{tm1b(EUCOMM)Hmgu}/Vps4a⁺
• Genetic Background: C57BL/6N-Vps4a^{tm1b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0779_2_A10

Data Sources

IMPC Data for Vps4a

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

tremors ( J:211773 )

IMPC - BCM

growth/size/body

enlarged spleen ( J:211773 )

♂

IMPC - BCM

increased spleen weight ( J:211773 )

♂

IMPC - BCM

hematopoietic system

enlarged spleen ( J:211773 )

♂

IMPC - BCM

increased spleen weight ( J:211773 )

♂

IMPC - BCM

immune system

enlarged spleen ( J:211773 )

♂

IMPC - BCM

increased spleen weight ( J:211773 )

♂

IMPC - BCM

integument

abnormal skin morphology ( J:211773 )

♂

IMPC - BCM

vision/eye

abnormal lens morphology ( J:211773 )

IMPC - BCM

cataract ( J:211773 )

IMPC - BCM