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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gria1tm7Rlh
targeted mutation 7, Richard L Huganir
MGI:5562310
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gria1tm7Rlh/Gria1tm7Rlh involves: 129S6/SvEvTac * C57BL/6 MGI:5562313


Genotype
MGI:5562313
hm1
Allelic
Composition		 Gria1tm7Rlh/Gria1tm7Rlh
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gria1tm7Rlh mutation (1 available); any Gria1 mutation (65 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:172128 )
N
• mice exhibit normal basal synaptic transmission
abnormal long-term potentiation ( J:172128 )
• long term potentiation induction threshold is reduced compared to in wild-type mice
• mice exhibit long term potentiation induced with spike-timing-dependent plasticity protocols at a long pre-post interval that is subthreshold for wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory