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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Jak2m1Dlbr
mutation 1, Dwayne L Barber
MGI:5562422
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Jak2m1Dlbr/Jak2m1Dlbr involves: 129S1/SvImJ * C57BL/6J MGI:5562426
ht2
Jak2m1Dlbr/Jak2+ involves: 129S1/SvImJ * C57BL/6J MGI:5562425
ht3
Jak2m1Dlbr/Jak2tm1Jni involves: 129P2/OlaHsd * 129S1/SvImJ * C57BL/6J MGI:5562428


Genotype
MGI:5562426
hm1
Allelic
Composition
Jak2m1Dlbr/Jak2m1Dlbr
Genetic
Background
involves: 129S1/SvImJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jak2m1Dlbr mutation (0 available); any Jak2 mutation (59 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

hematopoietic system
• at E12.5




Genotype
MGI:5562425
ht2
Allelic
Composition
Jak2m1Dlbr/Jak2+
Genetic
Background
involves: 129S1/SvImJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jak2m1Dlbr mutation (0 available); any Jak2 mutation (59 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
N
• bone marrow exhibits normal CFU-megakaryocyte assays
• mice exhibit normal response to 5-fluorouracil and phenylhydrazine challenge
• in female, but not male, mice at 8 weeks
• thrombocythemia in male and female mice at 8 weeks




Genotype
MGI:5562428
ht3
Allelic
Composition
Jak2m1Dlbr/Jak2tm1Jni
Genetic
Background
involves: 129P2/OlaHsd * 129S1/SvImJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jak2m1Dlbr mutation (0 available); any Jak2 mutation (59 available)
Jak2tm1Jni mutation (0 available); any Jak2 mutation (59 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

hematopoietic system
• at E12.5 and E14.5





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory