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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Bcl2l11tm6.1Boui
targeted mutation 6.1, Philippe Bouillet
MGI:5562690
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Bcl2l11tm6.1Boui/Bcl2l11tm6.1Boui
Foxp3tm4(YFP/icre)Ayr/Foxp3+ 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL MGI:5562712


Genotype
MGI:5562712
cn1
Allelic
Composition		 Bcl2l11tm6.1Boui/Bcl2l11tm6.1Boui
Foxp3tm4(YFP/icre)Ayr/Foxp3+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bcl2l11tm6.1Boui mutation (1 available); any Bcl2l11 mutation (36 available)
Foxp3tm4(YFP/icre)Ayr mutation (2 available); any Foxp3 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
increased regulatory T cell number ( J:208318 )
• increased frequency at 2 months that may be due to increased thymic output
• further increase at 6 months as in Bcl2l11tm1.1Ast homozygotes

immune system
increased regulatory T cell number ( J:208318 )
• increased frequency at 2 months that may be due to increased thymic output
• further increase at 6 months as in Bcl2l11tm1.1Ast homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory