Phenotypes associated with this allele

• Allele Symbol: Iqsec3^{tm3b(KOMP)Wtsi}
• Allele Name: targeted mutation 3b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5563212
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Iqsec3^tm3b(KOMP)Wtsi/Iqsec3^tm3b(KOMP)Wtsi	C57BL/6N-Iqsec3^tm3b(KOMP)Wtsi/Bay	MGI:5757258

Genotype
MGI:5757258

hm1

• Allelic Composition: Iqsec3^{tm3b(KOMP)Wtsi}/Iqsec3^{tm3b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Iqsec3^{tm3b(KOMP)Wtsi}/Bay
• Cell Lines: EPD0085_7_C11

Data Sources

IMPC Data for Iqsec3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

♂

IMPC - BCM

behavior/neurological

decreased thigmotaxis ( J:211773 )

♀

IMPC - BCM

decreased locomotor activity ( J:211773 )

♀

IMPC - BCM

growth/size/body

decreased lean body mass ( J:211773 )

♂

IMPC - BCM

decreased body length ( J:211773 )

♂

IMPC - BCM

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

♂

IMPC - BCM

impaired glucose tolerance ( J:211773 )

♂

IMPC - BCM

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - BCM

skeleton

decreased bone mineral content ( J:211773 )

♂

IMPC - BCM

decreased bone mineral density ( J:211773 )

♂

IMPC - BCM

vision/eye

abnormal retina inner nuclear layer morphology ( J:211773 )

♀

IMPC - BCM

decreased total retina thickness ( J:211773 )

♀

IMPC - BCM