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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Inpp5dm1Anu
mutation 1, Australian National University
MGI:5563462
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Inpp5dm1Anu/Inpp5dm1Anu C57BL/6JAnu-Inpp5dm1Anu MGI:5564957


Genotype
MGI:5564957
hm1
Allelic
Composition		 Inpp5dm1Anu/Inpp5dm1Anu
Genetic
Background		 C57BL/6JAnu-Inpp5dm1Anu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Inpp5dm1Anu mutation (1 available); any Inpp5d mutation (94 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
respiratory system
lung hemorrhage ( J:104190 )
• scattered microhaemorrhages associated with pneumonia
lung inflammation ( J:104190 )
• intra-alveolar acidophilic macrophage pneumonia with scattered microhaemorrhages
• superimposed recent suppurative bronchiolar pneumonia with microabscesses and early bronchitis

neoplasm
increased B cell derived lymphoma incidence ( J:104190 )
• histiocytic (B cell) lymphoma involving mediastinal lymph nodes, lung, spleen and small intestine

cardiovascular system
lung hemorrhage ( J:104190 )
• scattered microhaemorrhages associated with pneumonia

immune system
lung inflammation ( J:104190 )
• intra-alveolar acidophilic macrophage pneumonia with scattered microhaemorrhages
• superimposed recent suppurative bronchiolar pneumonia with microabscesses and early bronchitis




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory