All Phenotypes Dock8<m2Anu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Dock8^m2Anu
mutation 2, Australian National University
MGI:5563483

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dock8^m2Anu/Dock8^m2Anu	C57BL/6NCrlAnu-Dock8^m2Anu	MGI:5565198

Allelic Composition	Dock8^m2Anu/Dock8^m2Anu
Genetic Background	C57BL/6NCrlAnu-Dock8^m2Anu

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dock8^m2Anu mutation (2 available); any Dock8 mutation (103 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

absent marginal zone B cells ( J:104190 )

• in the spleen

decreased T cell number ( J:104190 )

• in peripheral blood

decreased activated T cell number ( J:104190 )

• activated CD8+ T cells

decreased IgM level ( J:104190 )

• on mature B cells

hematopoietic system