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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dock8m1Anu
mutation 1, Australian National University
MGI:5563486
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dock8m1Anu/Dock8m1Anu C57BL/6NCrlAnu-Dock8m1Anu MGI:5565197


Genotype
MGI:5565197
hm1
Allelic
Composition		 Dock8m1Anu/Dock8m1Anu
Genetic
Background		 C57BL/6NCrlAnu-Dock8m1Anu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dock8m1Anu mutation (2 available); any Dock8 mutation (103 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased T cell number ( J:104190 )
• in peripheral blood
decreased activated T cell number ( J:104190 )
• activated CD8+ T cells
decreased IgM level ( J:104190 )
• on mature B cells

hematopoietic system
decreased T cell number ( J:104190 )
• in peripheral blood
decreased activated T cell number ( J:104190 )
• activated CD8+ T cells
decreased IgM level ( J:104190 )
• on mature B cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory