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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dock2m2Anu
mutation 2, Australian National University
MGI:5563490
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dock2m2Anu/Dock2m2Anu C57BL/6JAnu-Dock2m2Anu MGI:5564959


Genotype
MGI:5564959
hm1
Allelic
Composition		 Dock2m2Anu/Dock2m2Anu
Genetic
Background		 C57BL/6JAnu-Dock2m2Anu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dock2m2Anu mutation (2 available); any Dock2 mutation (143 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased mature B cell number ( J:104190 )
• in peripheral blood
abnormal T cell morphology ( J:104190 )
• reduced CD44 protein expression on CD4+ and CD8+ cells
decreased T cell number ( J:104190 )
• in peripheral blood

immune system
decreased mature B cell number ( J:104190 )
• in peripheral blood
abnormal T cell morphology ( J:104190 )
• reduced CD44 protein expression on CD4+ and CD8+ cells
decreased T cell number ( J:104190 )
• in peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory