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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Xylt1npo
napoleon
MGI:5563785
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Xylt1npo/Xylt1npo involves: C57BL/6J * FVB/NJ MGI:5565182


Genotype
MGI:5565182
hm1
Allelic
Composition
Xylt1npo/Xylt1npo
Genetic
Background
involves: C57BL/6J * FVB/NJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Xylt1npo mutation (1 available); any Xylt1 mutation (37 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• fewer than expected mice are present at weaning

skeleton
N
• chondrocyte proliferation is normal
• cortical bones exhibit normal morphology
• at E16.5
• at E14.5, E16.5 and E18.5
• in adult mice
• at E14.5, E16.5 and E18.5
• in adult mice
• short and thick
• in adult mice
• decreased radius of the endosteal and periosteal radius
• more rapidly maturing chondrocytes compared with wild-type mice
• decreased radius
• with increased spacing
• in prehypertrophic and hypertrophic domains
• suggested by reduced skeletal element length
• of the talus at E18.5 and cervical vertebrae at E16.5

growth/size/body
N
• crown to rump length at E16.5 is normal

craniofacial
• at E16.5

cellular
• more rapidly maturing chondrocytes compared with wild-type mice

immune system
• more rapidly maturing chondrocytes compared with wild-type mice

limbs/digits/tail
• short at E14.5 and E16.5
• at E14.5, E16.5 and E18.5
• in adult mice
• short at E14.5 and E16.5
• at E14.5, E16.5 and E18.5
• in adult mice
• short at E14.5 and E16.5
• short at E14.5 and E16.5
• at E18.5 and worse in adulthood
• rhizomelic shortening in adult mice

hematopoietic system
• more rapidly maturing chondrocytes compared with wild-type mice





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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory