About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mtch2tm2.1Atgr
targeted mutation 2.1, Atan Gross
MGI:5566665
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Mtch2tm2Atgr/Mtch2tm2.1Atgr
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA MGI:5566667


Genotype
MGI:5566667
cn1
Allelic
Composition		 Mtch2tm2Atgr/Mtch2tm2.1Atgr
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mtch2tm2.1Atgr mutation (0 available); any Mtch2 mutation (26 available)
Mtch2tm2Atgr mutation (0 available); any Mtch2 mutation (26 available)
Speer6-ps1Tg(Alb-cre)21Mgn mutation (6 available); any Speer6-ps1 mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
liver/biliary system
liver failure ( J:209127 )
• resistant to liver failure caused by intraperitoneal injection of anti-FAS antibody
• recruitment of tBID to liver mitochondria is reduced




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory