Phenotypes associated with this allele

• Allele Symbol: Hsd11b1^tm1.1Awhi
• Allele Name: targeted mutation 1.1, Anne White
• Allele ID: MGI:5566777
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hsd11b1^tm1.1Awhi/Hsd11b1^tm1.1Awhi	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:5566780

Genotype
MGI:5566780

hm1

• Allelic Composition: Hsd11b1^tm1.1Awhi/Hsd11b1^tm1.1Awhi
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased food intake ( J:207713 )

• in mice fed a high fat diet

growth/size/body

growth/size/body region phenotype ( J:207713 )

N • mice fed a high fat diet exhibit normal increase in weight and changes in body composition

N • mice fed a high fat diet and treated with 11beta-hydroxysteroid dehydrogenase type 1 inhibitors respond the same as control mice

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:207713 )

N • mice fed a high fat diet exhibit normal changed in glucose metabolism

N • mice fed a high fat diet and treated with 11beta-hydroxysteroid dehydrogenase type 1 inhibitors respond the same as control mice