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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mesdtm2.1Bch
targeted mutation 2.1, Bernadette C Holdener
MGI:5568739
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mesdtm2.1Bch/Mesdtm2.1Bch involves: C57BL/6 * C57BL/6J MGI:5568741
ht2
 		Mesdtm1Bch/Mesdtm2.1Bch involves: 129 * C57BL/6 * C57BL/6J MGI:5568742
cx3
 		Mesdtm2.1Bch/Tyrc-3YPSd involves: 101/Rl * C3H/Rl * C57BL/6 * C57BL/6J MGI:5568743


Genotype
MGI:5568741
hm1
Allelic
Composition		 Mesdtm2.1Bch/Mesdtm2.1Bch
Genetic
Background		 involves: C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mesdtm2.1Bch mutation (0 available); any Mesd mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

The Mesdtm2.1Bch allele does not complement the Mesdtm1Bch and Tyrc-3YPSd alleles

embryo
small embryonic epiblast ( J:209024 )
• at E7.5 and E8.5
absent mesoderm ( J:209024 )
• mesoderm fails to differentiate




Genotype
MGI:5568742
ht2
Allelic
Composition		 Mesdtm1Bch/Mesdtm2.1Bch
Genetic
Background		 involves: 129 * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mesdtm1Bch mutation (1 available); any Mesd mutation (15 available)
Mesdtm2.1Bch mutation (0 available); any Mesd mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

The Mesdtm2.1Bch allele does not complement the Mesdtm1Bch and Tyrc-3YPSd alleles

embryo
small embryonic epiblast ( J:209024 )
• at E7.5 and E8.5
absent mesoderm ( J:209024 )
• mesoderm fails to differentiate




Genotype
MGI:5568743
cx3
Allelic
Composition		 Mesdtm2.1Bch/Tyrc-3YPSd
Genetic
Background		 involves: 101/Rl * C3H/Rl * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mesdtm2.1Bch mutation (0 available); any Mesd mutation (15 available)
Tyrc-3YPSd mutation (1 available); any Tyr mutation (379 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

The Mesdtm2.1Bch allele does not complement the Mesdtm1Bch and Tyrc-3YPSd alleles

embryo
small embryonic epiblast ( J:209024 )
• at E7.5 and E8.5
absent mesoderm ( J:209024 )
• mesoderm fails to differentiate




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory