All Phenotypes Mesd<tm2.1Bch> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mesd^tm2.1Bch
targeted mutation 2.1, Bernadette C Holdener
MGI:5568739

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mesd^tm2.1Bch/Mesd^tm2.1Bch	involves: C57BL/6 * C57BL/6J	MGI:5568741
ht2	Mesd^tm1Bch/Mesd^tm2.1Bch	involves: 129 * C57BL/6 * C57BL/6J	MGI:5568742
cx3	Mesd^tm2.1Bch/Tyr^c-3YPSd	involves: 101/Rl * C3H/Rl * C57BL/6 * C57BL/6J	MGI:5568743

Allelic Composition	Mesd^tm2.1Bch/Mesd^tm2.1Bch
Genetic Background	involves: C57BL/6 * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mesd^tm2.1Bch mutation (0 available); any Mesd mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

The Mesd^tm2.1Bch allele does not complement the Mesd^tm1Bch and Tyr^c-3YPSd alleles

embryo

failure to gastrulate ( J:209024 )

small embryonic epiblast ( J:209024 )

• at E7.5 and E8.5

absent mesoderm ( J:209024 )

• mesoderm fails to differentiate

Allelic Composition	Mesd^tm1Bch/Mesd^tm2.1Bch
Genetic Background	involves: 129 * C57BL/6 * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mesd^tm1Bch mutation (1 available); any Mesd mutation (15 available)
Mesd^tm2.1Bch mutation (0 available); any Mesd mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

The Mesd^tm2.1Bch allele does not complement the Mesd^tm1Bch and Tyr^c-3YPSd alleles

embryo

failure to gastrulate ( J:209024 )

small embryonic epiblast ( J:209024 )

• at E7.5 and E8.5

absent mesoderm ( J:209024 )

• mesoderm fails to differentiate

Allelic Composition	Mesd^tm2.1Bch/Tyr^c-3YPSd
Genetic Background	involves: 101/Rl * C3H/Rl * C57BL/6 * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mesd^tm2.1Bch mutation (0 available); any Mesd mutation (15 available)
Tyr^c-3YPSd mutation (1 available); any Tyr mutation (379 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

The Mesd^tm2.1Bch allele does not complement the Mesd^tm1Bch and Tyr^c-3YPSd alleles

embryo

failure to gastrulate ( J:209024 )

small embryonic epiblast ( J:209024 )

• at E7.5 and E8.5

absent mesoderm ( J:209024 )

• mesoderm fails to differentiate

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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