homeostasis/metabolism
N |
• mice fed standard chow exhibit normal blood glucose levels, glucose tolerance and insulin sensitivity
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• stimulated by glucose in mice fed a high fat diet
• reduced pancreatic insulin content in mice fed a high fat diet treated with STZ
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• in mice treated with STZ
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• in mice treated with STZ
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• in mice fed a high fat diet
• however, mice fed standard chow exhibit normal glucose tolerance
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endocrine/exocrine glands
• in mice fed a high fat diet
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• decreased individual islet size and total islet area in mice fed a high fat diet
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• increased beta cell apoptosis in mice fed a high fat diet
• beta cells exhibit increased sensitivity to cytokine-induced cell death compared with wild-type cells
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• in mice fed a high fat diet
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• stimulated by glucose in mice fed a high fat diet
• reduced pancreatic insulin content in mice fed a high fat diet treated with STZ
|
cellular
• in mice fed a high fat diet
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