About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Dcbld2tm1Mhms
targeted mutation 1, Mehran M Sadeghi
MGI:5569303
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Dcbld2tm1Mhms/Dcbld2tm1.1Mhms
Tg(Cdh5-cre)7Mlia/0
involves: 129S6/SvEvTac * C57BL/6J * FVB/N MGI:5569330


Genotype
MGI:5569330
cn1
Allelic
Composition
Dcbld2tm1Mhms/Dcbld2tm1.1Mhms
Tg(Cdh5-cre)7Mlia/0
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dcbld2tm1.1Mhms mutation (0 available); any Dcbld2 mutation (48 available)
Dcbld2tm1Mhms mutation (0 available); any Dcbld2 mutation (48 available)
Tg(Cdh5-cre)7Mlia mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Decreased retinal angiogenesis in Dcbld2tm1Mhms/Dcbld2tm1.1Mhms Tg(Cdh5-cre)7Mlia/0 mice

cardiovascular system
• at P5, retinal blood vessels exhibit reduced total length and number of branches compared to in wild-type mice
• reduced pericyte staining
• at P5, retinal blood vessels exhibit reduced total length and number of branches compared to in wild-type mice

vision/eye
• at P5, retinal blood vessels exhibit reduced total length and number of branches compared to in wild-type mice





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/29/2024
MGI 6.24
The Jackson Laboratory