Phenotypes associated with this allele

• Allele Symbol: Tg(Myh6-Mylk3)3Hkas
• Allele Name: transgene insertion 3, Hideko Kasahara
• Allele ID: MGI:5569925
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Myh6-Mylk3)3Hkas/0	Not Specified	MGI:5569930

Genotype
MGI:5569930

tg1

• Allelic Composition: Tg(Myh6-Mylk3)3Hkas/0
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

decreased response of heart to induced stress ( J:210147 )

• following transverse aortic constriction (TAC), mice exhibit less of an increase in heart weight, increased fractional shortening, preserved cardiac function, reduced cardiomyocytes apoptosis, reduced cardiomyocytes cell size and decreased end-systolic and end-diastolic pressure compared with wild-type mice

• however, mice subjected to TAC exhibit increased left ventricle systolic pressure

homeostasis/metabolism

decreased response of heart to induced stress ( J:210147 )

• following transverse aortic constriction (TAC), mice exhibit less of an increase in heart weight, increased fractional shortening, preserved cardiac function, reduced cardiomyocytes apoptosis, reduced cardiomyocytes cell size and decreased end-systolic and end-diastolic pressure compared with wild-type mice

• however, mice subjected to TAC exhibit increased left ventricle systolic pressure