Phenotypes associated with this allele

• Allele Symbol: Tmem248^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5569952
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tmem248^tm1.1(KOMP)Vlcg/Tmem248^tm1.1(KOMP)Vlcg	C57BL/6N-Tmem248^tm1.1(KOMP)Vlcg/Ucd	MGI:5797871

Genotype
MGI:5797871

hm1

• Allelic Composition: Tmem248^{tm1.1(KOMP)Vlcg}/Tmem248^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Tmem248^{tm1.1(KOMP)Vlcg}/Ucd
• Cell Lines: 13171A-H6

Data Sources

IMPC Data for Tmem248

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

♂

IMPC - UCD

cardiovascular system

decreased heart weight ( J:211773 )

IMPC - UCD

digestive/alimentary system

abnormal cecum morphology ( J:211773 )

IMPC - UCD

enlarged cecum ( J:211773 )

IMPC - UCD

abnormal colon morphology ( J:211773 )

♀

IMPC - UCD

megacolon ( J:211773 )

IMPC - UCD

abnormal duodenum morphology ( J:211773 )

♀

IMPC - UCD

enlarged duodenum ( J:211773 )

IMPC - UCD

enlarged ileum ( J:211773 )

IMPC - UCD

abnormal jejunum morphology ( J:211773 )

♀

IMPC - UCD

distended jejunum ( J:211773 )

IMPC - UCD

endocrine/exocrine glands

enlarged adrenal glands ( J:211773 )

♀

IMPC - UCD

abnormal thymus morphology ( J:211773 )

♂

IMPC - UCD

small thymus ( J:211773 )

♂

IMPC - UCD

decreased thymus weight ( J:211773 )

♂

IMPC - UCD

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - UCD

small seminal vesicle ( J:211773 )

♂

IMPC - UCD

abnormal pancreas morphology ( J:211773 )

IMPC - UCD

absent pancreas ( J:211773 )

IMPC - UCD

growth/size/body

increased lean body mass ( J:211773 )

IMPC - UCD

decreased body length ( J:211773 )

IMPC - UCD

hematopoietic system

abnormal thymus morphology ( J:211773 )

♂

IMPC - UCD

small thymus ( J:211773 )

♂

IMPC - UCD

decreased thymus weight ( J:211773 )

♂

IMPC - UCD

decreased erythrocyte cell number ( J:211773 )

♂

IMPC - UCD

decreased hematocrit ( J:211773 )

♂

IMPC - UCD

increased monocyte cell number ( J:211773 )

IMPC - UCD

abnormal spleen morphology ( J:211773 )

♂

IMPC - UCD

small spleen ( J:211773 )

IMPC - UCD

homeostasis/metabolism

decreased circulating cholesterol level ( J:211773 )

♂

IMPC - UCD

increased circulating alkaline phosphatase level ( J:211773 )

♂

IMPC - UCD

immune system

abnormal thymus morphology ( J:211773 )

♂

IMPC - UCD

small thymus ( J:211773 )

♂

IMPC - UCD

decreased thymus weight ( J:211773 )

♂

IMPC - UCD

increased monocyte cell number ( J:211773 )

IMPC - UCD

abnormal spleen morphology ( J:211773 )

♂

IMPC - UCD

small spleen ( J:211773 )

IMPC - UCD

liver/biliary system

decreased liver weight ( J:211773 )

♂

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - UCD

reproductive system

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - UCD

small seminal vesicle ( J:211773 )

♂

IMPC - UCD

female infertility ( J:211773 )

♀

IMPC - UCD

skeleton

vertebral fusion ( J:211773 )

IMPC - UCD

increased bone mineral content ( J:211773 )

IMPC - UCD