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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Cma1-cre)#Roer
transgene insertion, Axel Roers
MGI:5572820
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Patz1tm1.2Welm/Patz1tm1.2Welm
Tg(Cma1-cre)#Roer/0 		involves: 129P2/OlaHsd * C57BL/6 MGI:5572831
cn2
 		Orai2tm1.1Itl/Orai2tm1.1Itl
Tg(Cma1-cre)#Roer/0 		involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N MGI:6358682


Genotype
MGI:5572831
cn1
Allelic
Composition		 Patz1tm1.2Welm/Patz1tm1.2Welm
Tg(Cma1-cre)#Roer/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Patz1tm1.2Welm mutation (0 available); any Patz1 mutation (55 available)
Tg(Cma1-cre)#Roer mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:209168 )
N
• mice exhibit normal numbers of peritoneal mast cells




Genotype
MGI:6358682
cn2
Allelic
Composition		 Orai2tm1.1Itl/Orai2tm1.1Itl
Tg(Cma1-cre)#Roer/0
Genetic
Background		 involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Orai2tm1.1Itl mutation (0 available); any Orai2 mutation (14 available)
Tg(Cma1-cre)#Roer mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased susceptibility to type I hypersensitivity reaction ( J:278536 )
• mice sensitized with anti-DNP IgE and then treated with a solution containing DNP-HSA to induce passive systemic anaphylactic reaction show exacerbated anaphylaxis compared to controls, with mice showing delayed body temperature recovery




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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory