Phenotypes associated with this allele

• Allele Symbol: hydro
• Allele Name: hydronephrosis
• Allele ID: MGI:5573166
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ot1	hydro/?	involves: Mlac:ICR	MGI:5573176

Genotype
MGI:5573176

ot1

• Allelic Composition: hydro/?
• Genetic Background: involves: Mlac:ICR

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

skeleton phenotype ( J:207131 )

♂N • mice exhibit normal osteocyte lacunar area

short femur ( J:207131 )

♂

short tibia ( J:207131 )

♂

abnormal bone marrow cavity morphology ( J:207131 )

♂ • expanded

decreased bone mineral density ( J:207131 )

♂ • reduced cortical bone mineral density

decreased trabecular bone volume ( J:207131 )

♂

abnormal compact bone morphology ( J:207131 )

♂ • decreased cortical bone moment of inertia

decreased compact bone area ( J:207131 )

♂

abnormal periosteum morphology ( J:207131 )

♂ • decreased cortical periosteal perimeter

decreased bone trabecula number ( J:207131 )

♂ • with increased separation and reduced calcification

decreased trabecular bone thickness ( J:207131 )

♂

decreased bone ossification ( J:207131 )

♂ • suppressed as indicated by a decrease in osteoblast surface without changes in osteoid surface or thickness

decreased bone resorption ( J:207131 )

♂ • suppressed as indicated by reduced osteoclast surface and eroded surface

decreased bone strength ( J:207131 )

♂

homeostasis/metabolism

decreased circulating calcium level ( J:207131 )

♂

increased circulating phosphate level ( J:207131 )

♂

renal/urinary system

hydronephrosis ( J:207131 )

♂

limbs/digits/tail

short femur ( J:207131 )

♂

short tibia ( J:207131 )

♂