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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cdkl5tm1.1Cogr
targeted mutation 1.1, Cornelius Gross
MGI:5573232
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Cdkl5tm1.1Cogr/Cdkl5+
Tg(Emx1-cre)#Ito/0 		involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * C57BL/6J MGI:5574070
cn2
 		Cdkl5tm1.1Cogr/Y
Tg(Emx1-cre)#Ito/0 		involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * C57BL/6J MGI:5574071
cn3
 		Cdkl5tm1.1Cogr/Y
Tg(dlx5a-cre)1Mekk/0 		involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * CD-1 MGI:5574068
cn4
 		Cdkl5tm1.1Cogr/?
Tg(dlx5a-cre)1Mekk/0 		involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * CD-1 MGI:5574069


Genotype
MGI:5574070
cn1
Allelic
Composition		 Cdkl5tm1.1Cogr/Cdkl5+
Tg(Emx1-cre)#Ito/0
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkl5tm1.1Cogr mutation (1 available); any Cdkl5 mutation (20 available)
Tg(Emx1-cre)#Ito mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:209635 )
N
• mice exhibit normal activity levels and a trend for decreased head tracking
limb grasping ( J:209635 )
• in some mice




Genotype
MGI:5574071
cn2
Allelic
Composition		 Cdkl5tm1.1Cogr/Y
Tg(Emx1-cre)#Ito/0
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkl5tm1.1Cogr mutation (1 available); any Cdkl5 mutation (20 available)
Tg(Emx1-cre)#Ito mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:209635 )
N
• mice exhibit normal activity levels and a trend for decreased head tracking
limb grasping ( J:209635 )
• in some mice




Genotype
MGI:5574068
cn3
Allelic
Composition		 Cdkl5tm1.1Cogr/Y
Tg(dlx5a-cre)1Mekk/0
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkl5tm1.1Cogr mutation (1 available); any Cdkl5 mutation (20 available)
Tg(dlx5a-cre)1Mekk mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:209635 )
N
• mice do not exhibit abnormal clasping or head tracking




Genotype
MGI:5574069
cn4
Allelic
Composition		 Cdkl5tm1.1Cogr/?
Tg(dlx5a-cre)1Mekk/0
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkl5tm1.1Cogr mutation (1 available); any Cdkl5 mutation (20 available)
Tg(dlx5a-cre)1Mekk mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:209635 )
N
• mice do not exhibit abnormal clasping or head tracking




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory