Phenotypes associated with this allele

• Allele Symbol: Smo^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5573269
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Smo^tm1b(KOMP)Wtsi/Smo^tm1b(KOMP)Wtsi	C57BL/6N-Smo^tm1b(KOMP)Wtsi/Bay	MGI:5757744
ht2	Smo^tm1b(KOMP)Wtsi/Smo^+	C57BL/6N-Smo^tm1b(KOMP)Wtsi/Bay	MGI:5757743

Genotype
MGI:5757744

hm1

• Allelic Composition: Smo^{tm1b(KOMP)Wtsi}/Smo^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Smo^{tm1b(KOMP)Wtsi}/Bay
• Cell Lines: EPD0663_4_H05

Data Sources

IMPC Data for Smo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal pericardium morphology ( J:211773 )

IMPC - BCM

embryo

abnormal embryo development ( J:211773 )

IMPC - BCM

abnormal embryo turning ( J:211773 )

IMPC - BCM

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - BCM

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

Genotype
MGI:5757743

ht2

• Allelic Composition: Smo^{tm1b(KOMP)Wtsi}/Smo⁺
• Genetic Background: C57BL/6N-Smo^{tm1b(KOMP)Wtsi}/Bay
• Cell Lines: EPD0663_4_H05

Data Sources

IMPC Data for Smo

cardiovascular system

increased heart rate variability ( J:211773 )

♀

IMPC - BCM

decreased heart rate ( J:211773 )

IMPC - BCM

prolonged RR interval ( J:211773 )

IMPC - BCM

integument

abnormal skin morphology ( J:211773 )

♂

IMPC - BCM