Phenotypes associated with this allele

• Allele Symbol: Fadd^{tm1e.1(KOMP)Wtsi}
• Allele Name: targeted mutation 1e.1, Wellcome Trust Sanger Institute
• Allele ID: MGI:5573271
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fadd^tm1e.1(KOMP)Wtsi/Fadd^tm1e.1(KOMP)Wtsi	C57BL/6N-Fadd^tm1e.1(KOMP)Wtsi/Ucd	MGI:5757075
ht2	Fadd^tm1e.1(KOMP)Wtsi/Fadd^+	C57BL/6N-Fadd^tm1e.1(KOMP)Wtsi/Ucd	MGI:5757074

Genotype
MGI:5757075

hm1

• Allelic Composition: Fadd^{tm1e.1(KOMP)Wtsi}/Fadd^{tm1e.1(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Fadd^{tm1e.1(KOMP)Wtsi}/Ucd
• Cell Lines: EPD0317_1_C03

Data Sources

IMPC Data for Fadd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal embryo size ( J:211773 )

IMPC - TCP

abnormal neural tube closure ( J:211773 )

IMPC - TCP

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - TCP

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

nervous system

abnormal neural tube closure ( J:211773 )

IMPC - TCP

Genotype
MGI:5757074

ht2

• Allelic Composition: Fadd^{tm1e.1(KOMP)Wtsi}/Fadd⁺
• Genetic Background: C57BL/6N-Fadd^{tm1e.1(KOMP)Wtsi}/Ucd
• Cell Lines: EPD0317_1_C03

Data Sources

IMPC Data for Fadd

adipose tissue

increased total body fat amount ( J:211773 )

♂

IMPC - TCP

growth/size/body

decreased lean body mass ( J:211773 )

♂

IMPC - TCP

reproductive system

abnormal uterus morphology ( J:211773 )

♀

IMPC - TCP