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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Kcna10tm1Lex
targeted mutation 1, Lexicon Genomics
MGI:5574085
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Kcna10tm1Lex/Kcna10tm1Lex involves: 129S/SvEvBrd * C57BL/6 MGI:5574086


Genotype
MGI:5574086
hm1
Allelic
Composition
Kcna10tm1Lex/Kcna10tm1Lex
Genetic
Background
involves: 129S/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcna10tm1Lex mutation (0 available); any Kcna10 mutation (26 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hearing/vestibular/ear
N
• mice do not exhibit circling behavior or overt balance problems
• as early as P30 with poorly formed waveforms and broad response peaks
• elevated threshold at 10 months
• in 3 of 6 mice at P30
• in 3 of 8 mice at 10 months

behavior/neurological
N
• mice do not exhibit circling behavior or overt balance problems

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
vestibular disease DOID:3426 J:210785





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory