Analysis Tools|
Allele Symbol Allele Name Allele ID |
Optntm1.2Jda targeted mutation 1.2, Jonathan D Ashwell MGI:5574310 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• Background Sensitivity: mice congenic on a C57BL/6 background are born in Mendelian ratios unlike mice on a mixed background that mostly die prior to E11.5
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| N |
• mice exhibit normal immune cell development, T and B cell activation and TNF- or LPS-mediated activation of cells of the innate immune system
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• Background Sensitivity: most mice on a mixed background die prior to E11.5 unlike mice on a congenic C57BL/6 background that are born in Mendelian ratios
• however, mice that survive are indistinguishable from wild-type mice
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| N |
• mice exhibit normal immune cell development, T and B cell activation and TNF- or LPS-mediated activation of cells of the innate immune system
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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