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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Galntl5tm1Nari
targeted mutation 1, Hisashi Narimatsu
MGI:5574442
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Galntl5tm1Nari/Galntl5+ involves: 129P2/OlaHsd * C57BL/6J MGI:5574447


Genotype
MGI:5574447
ht1
Allelic
Composition		 Galntl5tm1Nari/Galntl5+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Galntl5tm1Nari mutation (0 available); any Galntl5 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Deformed or ventral flexuous sperm in Galntl5tm1Nari/Galntl5+ males

reproductive system
abnormal spermatogenesis ( J:206466 )
• abnormal loading of acrosomal proteins, such as acrosin, N-ethylamaleimide-sensitive factor and testicular angiotensin-converting enzyme, to spermatozoa
abnormal acrosome morphology ( J:206466 )
• absence of acrosomal proteins in acrosome and head of sperm
• testicular angiotensin-converting enzyme mislocalized to the sperm outer membrane
• absence of ubiquitin-proteasome system in neck region and acrosome of epididymal sperm

cellular
abnormal acrosome morphology ( J:206466 )
• absence of acrosomal proteins in acrosome and head of sperm
• testicular angiotensin-converting enzyme mislocalized to the sperm outer membrane
• absence of ubiquitin-proteasome system in neck region and acrosome of epididymal sperm




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory